Dosing and Administration

RIXUBIS fits your lifestyle with prophylactic or on‑demand dosing1

Watch the video for step-by-step instructions for the BAXJECT II® Needle-less Transfer device.

For step-by-step instructions on reconstituting RIXUBIS with the BAXJECT II Needle-less Transfer device, download the step-by-step guide.

Easy mixing with the BAXJECT II Needle-less Transfer device*

Step 1: Connect water vial. Step 2: Connect product vial. Step 3: Withdraw mixed product.

*As compared to needles, the BAXJECT II device is needle-less and has a one-piece design.

BAXJECT II Needle-less Transfer device information

Rx Only. For safe and proper use of this device, please refer to the instructions for use. The BAXJECT II device is intended for use with a single vial of product and is for single use only. Therefore, reconstitution and withdrawing a second vial requires a second BAXJECT II device.

Selected Important Risk Information for RIXUBIS [Coagulation Factor IX (Recombinant)]

If you have risk factors for developing blood clots, the use of factor IX products may increase the risk of abnormal blood clots.

Common side effects that have been reported with RIXUBIS include: unusual taste in the mouth, limb pain, and atypical blood test results.

Fast infusion rate: Maximum infusion rate of 10 mL/minute Fast infusion rate: Maximum infusion rate of 10 mL/minute

Wide range of dosing options1

  • 5 dosage strengths provide the opportunity for single-vial dosing
  • Each dose is color-coded
  • 5 mL Sterile Water for Injection, USP (diluent)
5 Color-coded dosage strengths. 230 IU, 500 IU, 1000 IU, 2000 IU, 3000 IU.

Talk to your doctor about what dosage may be recommended for you.

Selected Important Risk Information for RIXUBIS [Coagulation Factor IX (Recombinant)]

Your healthcare provider will tell you how much RIXUBIS to use based on your weight, the severity of your hemophilia B, and where you are bleeding.

You may have to have blood tests done after getting RIXUBIS to be sure that your blood level of factor IX is high enough to clot your blood.

Small package size, easy to store1

  • Convenient for when you're on-the-go
  • Takes up minimal shelf space

How to store RIXUBIS

  • Store at refrigerated temperature (36°F to 46°F) or store at room temperature (not to exceed 86°F) for up to 36 months
  • Do not freeze. Do not use beyond the expiration date printed on the carton or vial
RIXUBIS [Coagulation Factor IX (Recombinant)] packaging
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Important Risk Information for RIXUBIS [Coagulation Factor IX (Recombinant)]

Please read below for Indications and Detailed Important Risk Information for RIXUBIS. See full Prescribing Information.

Indications for RIXUBIS [Coagulation Factor IX (Recombinant)]

RIXUBIS is an injectable medicine used to replace clotting factor IX that is missing in adults and children with hemophilia B (also called congenital factor IX deficiency or Christmas disease).

RIXUBIS is used to control and prevent bleeding in people with hemophilia B. Your healthcare provider may give you RIXUBIS when you have surgery. RIXUBIS can reduce the number of bleeding episodes when used regularly (prophylaxis).

Detailed Important Risk Information for RIXUBIS [Coagulation Factor IX (Recombinant)]

You should not use RIXUBIS if you are allergic to hamsters or any ingredients in RIXUBIS.

You should tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines, such as over-the-counter medicines, supplements or herbal remedies, have any allergies, including allergies to hamsters, are nursing, are pregnant or planning to become pregnant, or have been told that you have inhibitors to factor IX.

Allergic reactions have been reported with RIXUBIS. Call your healthcare provider or get emergency treatment right away if you get a rash or hives, itching, tightness of the throat, chest pain or tightness, difficulty breathing, lightheadedness, dizziness, nausea, or fainting.

Your body may form inhibitors to factor IX. An inhibitor is part of the body's defense system. If you form inhibitors, it may stop RIXUBIS from working properly. Consult with your healthcare provider to make sure you are carefully monitored with blood tests for development of inhibitors to factor IX.

If you have risk factors for developing blood clots, the use of factor IX products may increase the risk of abnormal blood clots.

Common side effects that have been reported with RIXUBIS include: unusual taste in the mouth, limb pain, and atypical blood test results.

Call your healthcare provider right away about any side effects that bother you or if your bleeding does not stop after taking RIXUBIS.

Please see RIXUBIS full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.