2X weekly dosing can help align factor levels with the times you are physically active1
Talk to your doctor about which infusion days and dosage may be recommended for you. Your doctor will determine your dosage based on your age, weight, and bleeding pattern.
Many patients (24 out of 56) taking RIXUBIS® did not bleed over the course of the clinical study1
The efficacy and safety of RIXUBIS were evaluated in a prospective, open-label, uncontrolled, multicenter study of 73 male previously treated patients (PTPs) with severe or moderately severe hemophilia B who received RIXUBIS either for routine prophylaxis or on-demand treatment.6
- In this study, many patients experienced 0 bleeds with RIXUBIS twice-weekly for a mean treatment duration of 6.2 months.6
Routine prophylactic treatment helped patients achieve a low Annualized Bleed Rate (ABR)*1
Median ABR (range: 0.0-15.6)
Median ABR (range: 0.0-21.5)
*The majority of patients ≥12 years taking RIXUBIS had joint disease (88%) and target joints (66%) at screening.1
Know Your Annual Bleed Rate (ABR): Annual bleed rate is the number of bleeds a person experiences over the course of one year. If you don't have a year's worth of bleeds tracked, simply take the number of bleeds that you had in the last month and multiply by 12 as an estimate, which is your annualized bleed rate (ABR).
Most bleeds (211 out of 249) were resolved with 1 to 2 infusions1
With RIXUBIS, 96% of bleeding episodes were rated as having excellent or good bleed resolution.*1
*Excellent is defined as full relief of pain and cessation of objective signs of bleeding after a single infusion; no additional infusion is required for the control of bleeding; Good is defined as definite pain relief and/or improvement in signs of bleeding after a single infusion; possibly requires more than one infusion for complete resolution.
Selected Important Risk Information for RIXUBIS[Coagulation Factor IX (Recombinant)]
Allergic reactions have been reported with RIXUBIS. Call your healthcare provider or get emergency treatment right away if you get a rash or hives, itching, tightness of the throat, chest pain or tightness, difficulty breathing, lightheadedness, dizziness, nausea, or fainting.
Your body may form inhibitors to factor IX. An inhibitor is part of the body’s defense system. If you form inhibitors, it may stop RIXUBIS from working properly. Consult with your healthcare provider to make sure you are carefully monitored with blood tests for development of inhibitors to factor IX.
The clinical trial demonstrated that recovery levels were consistent over time across all patient groups at week 261
WHAT DOES RECOVERY MEAN?
Recovery is the name for the relative amount of factor IX in the bloodstream immediately after infusing. An average recovery is about 50%.3 Factor levels gradually decrease following infusion. Recovery is important to know because it helps your doctor determine the proper dose of factor your body needs and is measured by taking a blood test, also called an assay.3 Recovery is different for every person and may change for you over time. It can be influenced by age and weight and differs based on the factor product used.4,5
Talk to your doctor about what recovery levels mean for you.