2X weekly dosing can help align factor levels with the times you are physically active1
Talk to your doctor about which infusion days and dosage may be recommended for you. Your doctor will determine your dosage based on your age, weight, and bleeding pattern.
Many patients (9 out of 23) taking RIXUBIS® did not bleed over the course of the clinical study1
In the pediatric study, the efficacy and safety of RIXUBIS were evaluated in 23 male previously treated patients (PTPs) with severe or moderately severe hemophilia B. Patients between 1.8 and 11.8 years of age (median age 7.10 years), with 11 subjects <6 years of age, received RIXUBIS for routine prophylaxis and control of bleeding episodes for a mean treatment duration of 7.7 months.1,2
- In this study, many patients experienced 0 bleeds with twice-weekly RIXUBIS prophylaxis.2
Routine prophylactic treatment helped patients achieve a low annualized bleed rate (ABR)1
Median ABR (range: 0.0-2.0)
Median ABR (range: 0.0-7.2)
Know Your Annual Bleed Rate (ABR): Annual bleed rate is the number of bleeds a person experiences over the course of one year. If you don't have a year's worth of bleeds tracked, simply take the number of bleeds that you had in the last month and multiply by 12 as an estimate, which is your annualized bleed rate.
Most bleeds (23 out of 26) were resolved with 1 to 2 infusions1
With RIXUBIS, 96.2% of bleeding episodes were rated as having excellent or good bleed resolution.*1
*Excellent is defined as full relief of pain and cessation of objective signs of bleeding after a single infusion; no additional infusion is required for the control of bleeding; Good is defined as definite pain relief and/or improvement in signs of bleeding after a single infusion; possibly requires more than one infusion for complete resolution.
Selected Important Risk Information for RIXUBIS [Coagulation Factor IX (Recombinant)]
You should not use RIXUBIS if you are allergic to hamsters or any ingredients in RIXUBIS.
You should tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines, such as over-the-counter medicines, supplements or herbal remedies, have any allergies, including allergies to hamsters, are nursing, are pregnant or planning to become pregnant, or have been told that you have inhibitors to factor IX.
The clinical trial demonstrated that recovery levels were consistent over time across all patient groups1
WHAT DOES RECOVERY MEAN?
Recovery is the name for the relative amount of factor IX in the bloodstream immediately after infusing. An average recovery is about 50%.3 Factor levels gradually decrease following infusion. Recovery is important to know because it helps your doctor determine the proper dose of factor your body needs and is measured by taking a blood test, also called an assay.3 Recovery is different for every person and may change for you over time. It can be influenced by age and weight and differs based on the factor product used.4,5
Talk to your doctor about what recovery levels mean for you.